Rienden provides peptide library service. Here are some useful information about different kind of peptide library. You can contact us to learn more information about custom peptide synthesis service and peptide library. Request a quotation, please click here. Peptide case study, please click here.
Overlapping peptide library is generated by breaking the original protein or peptide into many equal-length overlapping fragment and it is used for linear, continuous epitope mapping and T-cell epitope determination.
Example: RILCGSSWNVLDFEISGKLGEHVIVLVVAK(30AA protein)
Peptide length: 10 mer
No. Peptide 5
Alanine Scanning Library: Generation of peptide library in which alanine(Ala,A) is systematically substituted into each of the amino acids in the identified peptide sequence (epitope)
Selected position in a peptide sequence is systematically replaced with different amino acids to determine the preferred amino acid residues at these positions, as manifested by corresponding increases in activity
Truncation Library: Series of peptide sequences representing the systematic truncation of the flanking residues to determine the minimum length required for optimum peptide activity
Random Library is similar to positional scanning library. It’s constructed by substituting selected positions on the original peptide randomly and simultaneously with all other natural amino acids in a shot gun approach with a purpose to elucidate potential alternatives for enhanced peptide activity
Scramble peptide library
Scramble peptide library：Scramble Library is constructed by carrying out permutation on the original peptide’s sequence. It has the potential to give all possible alternatives and offers and represents the highest degree of variability for peptide library.
T-cell Truncated peptide library
T-cell Truncated peptide libraries：Allow the testing of all possible T-cell epitopes across a protein of interest